A three-dimensional index of the molecules inside the flower. Drag to rotate the field — select any compound to open its dossier.












Marijuana.Directory catalogs the cannabinoids inside the flower — their structures, receptor targets, and reported effects — grounded in the science and free of the hype. Every entry is a molecule you can turn over, read, and understand.
From the abundant to the trace. Search or filter, then select any card to open its full dossier.
Concentrated in the brain and nervous system, CB1 is the docking site behind THC’s psychoactivity and much of cannabis’ effect on mood and perception.
Found mainly in immune tissue and the periphery, CB2 is a target for anti-inflammatory effects without the intoxication of CB1 activation.
Cannabinoids and aromatic terpenes appear to modulate one another, so the whole-plant profile can shape an experience that isolated molecules do not.
The plant builds nearly every cannabinoid from a single acidic precursor. Heat then decarboxylates the acids into the neutral compounds we know.
Cannabinoids don’t act alone. Terpenes — the plant’s aromatic oils — shape aroma and flavor, and through the entourage effect they color the character of every strain.
How cannabis enters the body shapes how fast it arrives, how long it lasts, and how intense it feels.
Cannabis is traditionally sorted into three broad families, each with its own growth habit and reputation for effect.
Beyond the binary. Researchers increasingly find that a plant’s cannabinoid and terpene chemotype predicts how it feels far better than the indica / sativa label alone. Treat the families as a starting point, not a rule.
A snapshot of cannabis policy around the world. Laws shift quickly — always verify your local jurisdiction.
Cannabis appears in the pharmacopeia attributed to the Chinese emperor Shen Nung — among the earliest written accounts of its medicinal use.
Irish physician William O’Shaughnessy documents its therapeutic effects, sparking interest across Europe and North America.
Chemist Roger Adams isolates cannabidiol at the University of Illinois — the first cannabinoid to be characterized.
Raphael Mechoulam and Yechiel Gaoni isolate and map the structure of THC in Israel, pinpointing the source of the plant’s psychoactivity.
Researchers locate the CB1 receptor in the brain, revealing the biological system that cannabinoids act upon.
Scientists identify anandamide, an endocannabinoid the body produces itself — the natural counterpart to THC.
California’s Proposition 215 makes it the first US state to legalize cannabis for medical use.
Uruguay becomes the first country in the world to fully legalize and regulate recreational cannabis.
The US FDA approves Epidiolex, a CBD medicine, and Canada legalizes recreational cannabis nationwide.
Germany legalises adult use (2024) as Thailand returns to a medical-only model (2025). In 2026 the United States reclassifies FDA-approved and state-licensed medical cannabis to Schedule III — a first crack in federal prohibition, though recreational cannabis remains Schedule I.