← All compounds
Cannabinoid

CBD

Cannabidiol
C₂₁H₃₀O₂ 314.46 g/mol Non-intoxicating
Typical abundancemajor
Receptor targets

5-HT1A · TRPV1 · GPR55 · CB1/CB2 (negative allosteric modulator)

Mechanism of action

Acts on serotonin (5-HT1A) and vanilloid (TRPV1) receptors and dampens CB1 signalling as a negative allosteric modulator rather than a direct agonist, which is why it does not produce a 'high'.

Reported effects
AnticonvulsantAnxiolyticAnti-inflammatory
Common terpenes
Myrcene Limonene Linalool Caryophyllene
Research

Extensively studied; active ingredient of Epidiolex, FDA-approved (2018) for rare epilepsies including Dravet and Lennox-Gastaut syndromes.