CBDA

Cannabidiolic acid

C₂₂H₃₀O₄ 358.47 g/mol Non-intoxicating (raw)

Typical abundancemajor

Receptor targets

COX-2 (inhibitor) · 5-HT1A (agonist)

Mechanism of action

The raw acidic form of CBD. Inhibits COX-2 and is a potent 5-HT1A agonist, a pathway linked to anti-nausea effects in animal models. Converts to CBD on heating.

Reported effects

Anti-nausea (preclinical)Anti-inflammatory (preclinical)

Common terpenes

Linalool

Research

Preclinical; anti-nausea and anti-inflammatory activity in laboratory models.