HHC

Hexahydrocannabinol

C₂₁H₃₂O₂ 316.49 g/mol Intoxicating (milder)

Typical abundancetrace

Receptor targets

CB1 · CB2 partial agonist (9R-epimer active · 9S weak)

Mechanism of action

Hydrogenated THC — the C9=C10 double bond is saturated, creating 9R and 9S epimers. The 9R epimer binds CB1 with roughly THC-like affinity while the 9S epimer is much weaker.

Reported effects

Euphoria (milder)Relaxation

Common terpenes

Myrcene Limonene Linalool

Research

Present only in trace amounts naturally; market supply is semi-synthetic from hemp-derived CBD. Widely sold since 2021, with toxicology and clinical data still limited.